Workshop 1

The neuroinformatics of neuroanatomy

Neuroanatomy provides one of the unifying frameworks for neuroscience and thus it is not surprising that it provides the basis for many neuroinformatics tools and approaches.  Regardless of whether one is working at the subcellular, cellular or gross anatomical level or whether one is modeling circuitry, molecular pathways or function, at some point, this work will include an anatomical reference.  The brain is perhaps unique in the number of nomenclatures and strategies for parcellating its anatomy.  Yet this diversity creates a headache for current information systems, which must attempt to reconcile the different reference systems developed.  This workshop will focus on what is required of those working in neuroanatomy to make their data suitable for and compliant with neuroinformatics systems, so that it can be compared computationally to other work and reused by others, including those who are working in genomics, proteomics, physiology, and other forms of behavior.  Thus, the aim is to focus less on exactly how one parcellates a brain and more on how one models this parcellation to make the information usable.  We will hear from researchers working on informatics systems that include an atlasing component about their approaches and best practices.

Session: Monday, August 25th 10:20-12:10

Chair: Maryann Martone

Speakers:

Trygve Leergard - Navigating the rodent brain by digital atlasing

Jacopo Annese - The digital renaissance of human neuroanatomy

Douglas Bowden - Essential features of digital brain models for neuroinformatics

Mike Hawrylycz - Neuroinformatics and digital atlases of the Allen Institute for Brain Science